Prof Mohini Gray at the Centre for Inflammation Research at the University of Edinburgh is currently undertaking research into mechanisms of tertiary lymphoid structure in non-small cell lung cancer with Dr Ahsan Akram. Professor Gray’s research programme principally bridges clinical medicine and fundamental immunology to enhance understanding of immune processes, autoimmunity, and autoimmune disease pathogenesis. This specific collaborative research project has the potential to open new therapeutic pathways and positively impact patient care. Only a minority of patients respond to new therapies (called immunotherapy) which stimulate the body’s own immune system to fight cancer. This research project is investigating if cells called cancer-associated fibroblasts (CAFs) play a role in the success/failure of current treatments. This research will provide important information on the role of CAFs in lung cancer and may decide new combinations and targets of effective treatments.